Use of magnetic resonance imaging to analyze the performance of hollow-fiber bioreactors.

@article{Donoghue1992UseOM,
  title={Use of magnetic resonance imaging to analyze the performance of hollow-fiber bioreactors.},
  author={C M Donoghue and M Brideau and P Newcomer and Barry M. Pangrle and D. Dibiasio and Edmond Walsh and S Moore},
  journal={Annals of the New York Academy of Sciences},
  year={1992},
  volume={665},
  pages={285-300}
}
Preliminary experiments were described that demonstrate that MRI is an effective tool for the noninvasive study of hollow-fiber bioreactors. Flow-compensated velocity-encoding pulse sequences were successively applied to analyze the velocity patterns in a module operated without cells, with an artificially induced flow field perturbation. Diffusion damping pulse sequences were also used to spatially resolve regions of cell growth in a bioreactor. These experiments provide the necessary basis… CONTINUE READING