Use of log-linear analysis to construct explanatory models for TDBP- and AFB1-induced mutation spectra in lacI transgenic animals.

@article{Brackley1999UseOL,
  title={Use of log-linear analysis to construct explanatory models for TDBP- and AFB1-induced mutation spectra in lacI transgenic animals.},
  author={Moyra E Brackley and Johan G de Boer and Barry W. Glickman},
  journal={Mutation research},
  year={1999},
  volume={425 1},
  pages={55-69}
}
Mutation spectra recovered from lacI transgenic animals exposed in separate experiments to tris-(2,3-dibromopropyl)phosphate (TDBP) or aflatoxin B1 (AFB1) were examined using log-linear analysis. Log-linear analysis is a categorical procedure that analyses contingency table data. Expected contingency table cell counts are estimated by maximum likelihood as effects of main variables and variable interactions. Evaluation of hierarchical models of decreasing complexity indicates when significant… CONTINUE READING