Use of lateral flow assays to determine IP-10 and CCL4 levels in pleural effusions and whole blood for TB diagnosis.

@article{Sutherland2016UseOL,
  title={Use of lateral flow assays to determine IP-10 and CCL4 levels in pleural effusions and whole blood for TB diagnosis.},
  author={Jayne S. Sutherland and Joseph F Mendy and Awa Gindeh and Gerhard Walzl and Toyin Omotayo Togun and Olumuyiwa A. Owolabi and Simon A. Donkor and Martin O C Ota and Elisa Tjon Kon Fat and Tom H. M. Ottenhoff and Annemieke Geluk and Paul L A M Corstjens},
  journal={Tuberculosis},
  year={2016},
  volume={96},
  pages={31-6}
}
One of the key problems in combating TB is the lack of fast and accurate diagnostic tests that are affordable and easy to use in resource-limited settings. We have used a field-friendly up-converting phosphor (UCP) reporter technology in a lateral flow (LF) based test for the diagnosis of respiratory infections. In this study we analysed samples obtained from patients presenting with symptoms suggestive of TB but prior to confirmation by microbiology in The Gambia. Following clinical and… CONTINUE READING