Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology.

@article{Orange2006UseOI,
  title={Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology.},
  author={Jordan S Orange and Elham M. Hossny and Catherine R. Weiler and Mark C. Ballow and Melvin Berger and Francisco A. B. Bonilla and Rebecca Buckley and Javier Chinen and Yehia M. El-Gamal and Bruce D Mazer and Robert P. Nelson and Dhavalkumar D. Patel and Elizabeth Secord and Ricardo U. Sorensen and Richard L. Wasserman and Charlotte Cunningham-Rundles},
  journal={The Journal of allergy and clinical immunology},
  year={2006},
  volume={117 4 Suppl},
  pages={
          S525-53
        }
}
Human immunoglobulin prepared for intravenous administration (IGIV) has a number of important uses in the treatment of disease. Some of these are in diseases for which acceptable treatment alternatives do not exist. In this review we have evaluated the evidence underlying a wide variety of IGIV uses and make specific recommendations on the basis of these data. Given the potential risks and inherent scarcity of IGIV, careful consideration of the indications for and administration of IGIV is… CONTINUE READING
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