Use of in vitro models of bovine corneal endothelial cells to determine the relative toxicity of viscoelastic agents.

@article{Nguyen1992UseOI,
  title={Use of in vitro models of bovine corneal endothelial cells to determine the relative toxicity of viscoelastic agents.},
  author={L K Nguyen and Richard Yee and Stephanie Sigler and Hui Ye},
  journal={Journal of cataract and refractive surgery},
  year={1992},
  volume={18 1},
  pages={
          7-13
        }
}
Healon, Viscoat and Amvisc Plus (Amvisc+) are commercial preparations containing hyaluronic acids of different molecular weights and viscosities. Cytotoxicity of these preparations to the corneal endothelium may be a factor in postsurgical recovery of the cornea. Using different in vitro models of bovine corneal endothelial cells (BCEC), three experiments to compare the possible detrimental effects of these viscoelastic agents were designed. In the confluent model, confluent BCEC were exposed… CONTINUE READING

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