Use of human glandular kallikrein 2 for the detection of prostate cancer: preliminary analysis.

@article{Partin1999UseOH,
  title={Use of human glandular kallikrein 2 for the detection of prostate cancer: preliminary analysis.},
  author={Alan W. Partin and WilliamJ. Catalona and Judith A. Finlay and Claude Darte and Donald J. Tindall and Charles Y. F. Young and George G. Klee and Daniel Wai-Tin Chan and Harry G. Rittenhouse and Robert Lewis Wolfert and David L. Woodrum},
  journal={Urology},
  year={1999},
  volume={54 5},
  pages={
          839-45
        }
}
OBJECTIVES Human glandular kallikrein 2 (hK2) and prostate-specific antigen (PSA) are members of a multigene family of serine proteases that share approximately 80% sequence homology. Both are expressed in the prostate epithelium, are under androgen regulation, are present in serum and seminal fluid, and can form complexes with endogenous protease inhibitors (eg, alpha2-macroglobulin and alpha1-antichymotrypsin). Differences in immunohistochemistry and substrate specificity suggest hK2 may… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 61 CITATIONS

FILTER CITATIONS BY YEAR

2000
2018

CITATION STATISTICS

  • 4 Highly Influenced Citations

  • Averaged 2 Citations per year over the last 3 years

Similar Papers

Loading similar papers…