Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study.

  title={Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study.},
  author={Renee Heffron and Deborah Donnell and Helen V Rees and Connie L Celum and Nelly R. Mugo and Edwin Were and Guy de Bruyn and Edith Nakku-Joloba and Kenneth Ngure and James N Kiarie and Robert W. Coombs and Jared M Baeten},
  journal={The Lancet. Infectious diseases},
  volume={12 1},
BACKGROUND Hormonal contraceptives are used widely but their effects on HIV-1 risk are unclear. We aimed to assess the association between hormonal contraceptive use and risk of HIV-1 acquisition by women and HIV-1 transmission from HIV-1-infected women to their male partners. METHODS In this prospective study, we followed up 3790 heterosexual HIV-1-serodiscordant couples participating in two longitudinal studies of HIV-1 incidence in seven African countries. Among injectable and oral… CONTINUE READING
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Genital HIV-1 RNA levels predict risk of heterosexual HIV-1 transmission

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