Use of genome-wide expression profiling and mutagenesis to study the intestinal lifestyle of Campylobacter jejuni.

@article{Stintzi2005UseOG,
  title={Use of genome-wide expression profiling and mutagenesis to study the intestinal lifestyle of Campylobacter jejuni.},
  author={Alain P Stintzi and Denver D Marlow and Kiran Palyada and Hemant Naikare and Roger J. Panciera and Lisa C Whitworth and Cyril Clarke},
  journal={Infection and immunity},
  year={2005},
  volume={73 3},
  pages={1797-810}
}
Campylobacter jejuni is the most common bacterial cause of diarrhea worldwide. To colonize the gut and cause infection, C. jejuni must successfully compete with endogenous microbes for nutrients, resist host defenses, persist in the intestine, and ultimately infect the host. These challenges require the expression of a battery of colonization and virulence determinants. In this study, the intestinal lifestyle of C. jejuni was studied using whole-genome microarray, mutagenesis, and a rabbit… CONTINUE READING

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