Use of fluorine-containing stationary phases for the separation of an alkyl bromide from its hydrocarbon analog by high-performance liquid chromatography.

Abstract

Radiolabelled Sch 13835, an inhibitor of platelet derived growth factor, was prepared by catalytic hydrogenolysis of a benzyl bromide precursor with tritium gas. Regular and deactivated reversed-phase HPLC stationary phases gave poor peak shapes and little resolution of Sch 13835 and the benzyl bromide precursor. Fluorodecyl and fluoroether stationary… (More)

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@article{Hendershot1997UseOF, title={Use of fluorine-containing stationary phases for the separation of an alkyl bromide from its hydrocarbon analog by high-performance liquid chromatography.}, author={Shelley L. Hendershot and David Koharski and Patrick J. McNamara}, journal={Journal of chromatography. A}, year={1997}, volume={762 1-2}, pages={159-65} }