Use of epidemiological cutoff values to examine 9-year trends in susceptibility of Aspergillus species to the triazoles.

@article{Pfaller2011UseOE,
  title={Use of epidemiological cutoff values to examine 9-year trends in susceptibility of Aspergillus species to the triazoles.},
  author={Michael A. Pfaller and Linda B Boyken and Richard J. Hollis and Jennifer S. Kroeger and Shawn A. Messer and Shailesh Tendolkar and Daniel J. Diekema},
  journal={Journal of clinical microbiology},
  year={2011},
  volume={49 2},
  pages={586-90}
}
In the absence of clinical breakpoints, epidemiological cutoff values (ECVs) have been established to distinguish wild-type (WT) isolates of Aspergillus spp. from those that may harbor resistance mutations. Recently, the CLSI has developed ECVs for triazoles (itraconazole, posaconazole, and voriconazole) and common Aspergillus species. We applied the… CONTINUE READING