Use of enzyme-linked immunosorbent assay (ELISA) for detection and quantification of monoclonal antibodies.

  • G. Lewis
  • Published 1994 in Bio-medical materials and engineering

Abstract

The thrust of the present work is the demonstration of the feasibility of using an enzyme-linked immunosorbent assay (ELISA) for the detection and quantification of a monoclonal antibody human serum. The antibodies used, 7E3 and D3GP3, have been proposed as platelet receptor blockers, being directed specifically against the platelet membrane receptors (glycoprotein IIb/IIIa) and thus of significance in the management of patients at a very hgih risk of thrombotic occlusion. It is shown that 7E3 is more easily adsorbed than D3GP3 and hence has a higher potential for the stated application.

Cite this paper

@article{Lewis1994UseOE, title={Use of enzyme-linked immunosorbent assay (ELISA) for detection and quantification of monoclonal antibodies.}, author={G. Lewis}, journal={Bio-medical materials and engineering}, year={1994}, volume={4 5}, pages={363-7} }