Use of endothelium cultured on microcarriers as a model for the microcirculation.

@article{Busch1982UseOE,
  title={Use of endothelium cultured on microcarriers as a model for the microcirculation.},
  author={Christer Busch and Pasquale A. Cancilla and L E Debault and Jonathan C. Goldsmith and W. Garrett Owen},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1982},
  volume={47 5},
  pages={498-504}
}
The geometry of the vascular system is such that the surface area to volume ratio changes dramatically as a unit volume of blood circulates. Thus, it faces a surface area that is some 1000 times larger in the capillaries than in larger vessels. To approach the in vivo situation an in vitro model for the microcirculation was developed that uses endothelium cultured on microcarrier beads. Details of the culture method are presented. The cultures form confluent monolayers around the beads and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Deep vein thrombosis: pathogenesis, diagnosis, and medical management.

Cardiovascular diagnosis and therapy • 2017
View 1 Excerpt

Antithrombotic Agents in the Management of Sepsis.

Turkish journal of haematology : official journal of Turkish Society of Haematology • 2002
View 1 Excerpt

Similar Papers

Loading similar papers…