Use of electron paramagnetic resonance spectroscopy to evaluate the redox state in vivo.

  title={Use of electron paramagnetic resonance spectroscopy to evaluate the redox state in vivo.},
  author={H. Swartz and N. Khan and V. Khramtsov},
  journal={Antioxidants & redox signaling},
  volume={9 10},
  • H. Swartz, N. Khan, V. Khramtsov
  • Published 2007
  • Chemistry, Medicine
  • Antioxidants & redox signaling
  • The aim of this article is to provide an overview of how electron paramagnetic resonance (EPR) can be used to measure redox-related parameters in vivo. The values of this approach include that the measurements are made under fully physiological conditions, and some of the measurements cannot be made by other means. Three complementary approaches are used with in vivo EPR: the rate of reduction or reactions of nitroxides, spin trapping of free radicals, and measurements of thiols. All three… CONTINUE READING
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