Use of dithiothreitol to improve the diagnosis of prosthetic joint infections.

  title={Use of dithiothreitol to improve the diagnosis of prosthetic joint infections.},
  author={Lorenzo Drago and Valentina Signori and Elena de Vecchi and Christian Vassena and Elisa Palazzi and Laura Cappelletti and D. Roman{\`o} and Carlo Luca Roman{\`o}},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  volume={31 11},
Diagnosis of prosthetic joint infections (PJIs) remains a challenge for microbiologists, despite new techniques for bacteria isolation have been developed in recent years. A widely recognized standard method has not yet been indicated mainly because of limitations due difficult procedures and need of dedicated instrumentation. We evaluated the ability of a sulfhydryl compound routinely used in microbiology laboratories, dithiothreitol (DTT), to dislodge bacteria from biofilm, keeping them alive… CONTINUE READING


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