Use of deep brain stimulation in treatment-resistant depression.

  title={Use of deep brain stimulation in treatment-resistant depression.},
  author={Donald A. Malone},
  journal={Cleveland Clinic journal of medicine},
  volume={77 Suppl 3},
Deep brain stimulation has emerged as an experimental treatment option for the sizeable proportion of patients with major depression that is refractory to multiple medications and psychotherapy. Chronic stimulation of the ventral internal capsule/ventral striatum has been shown to improve function and mood in patients with severe obsessive-compulsive disorder, and has likewise been applied to patients with treatment-resistant depression. Multicenter experience with chronic deep brain… CONTINUE READING
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