Use of contiguous congenic strains in analyzing compound QTLs.

@article{Rapp2012UseOC,
  title={Use of contiguous congenic strains in analyzing compound QTLs.},
  author={John P. Rapp and Bina Joe},
  journal={Physiological genomics},
  year={2012},
  volume={44 2},
  pages={117-20}
}
Genetic analysis of polygenic traits in rats and mice has been very useful for finding the approximate chromosomal locations of the genes causing quantitative phenotypic variation, so-called quantitative trait loci (QTL). Further localization of the causative genes and their ultimate identification has, however, proven to be slow and frustrating. A major technique for gene identification in such models utilizes series of congenic strains with progressively smaller chromosomal segments… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Spurious linkage between markers in QTL mapping

Molecular Breeding • 2004
View 7 Excerpts
Highly Influenced

Reply to letter to the editor.

Journal of pediatric surgery • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…