Use of chemically patterned substrate to study directional effect of damaging electrical stimulation on cultured neuroblastoma cells

@article{Matsuzawa1994UseOC,
  title={Use of chemically patterned substrate to study directional effect of damaging electrical stimulation on cultured neuroblastoma cells},
  author={Mieko Matsuzawa and Richard S. Potember and Victor Krauthamer},
  journal={Brain Research},
  year={1994},
  volume={667},
  pages={47-53}
}
We used ordered arrangements of neuroblastoma cells in culture on chemically patterned substrates to direct the orientation of electrical stimulation with respect to cell alignment. Chemically patterned parallel lines of self-assembled monolayer films were fabricated on glass substrates via a deep UV lithographic procedure. Cultured neuroblastoma cells deposited on these substrates formed long (approximately 300 microns in length) neuritic processes along the patterned lines in the presence of… CONTINUE READING