Use of checkerboard DNA-DNA hybridization to study complex microbial ecosystems.

@article{Socransky2004UseOC,
  title={Use of checkerboard DNA-DNA hybridization to study complex microbial ecosystems.},
  author={Sigmund Sidney Socransky and Anne D. Haffajee and Corrine O. Smith and Ludovic Martin and Jessica A Haffajee and Naciye Guzin Uzel and J Max Goodson},
  journal={Oral microbiology and immunology},
  year={2004},
  volume={19 6},
  pages={352-62}
}
It has been difficult to conduct large scale studies of microbiologically complex ecosystems using conventional microbiological techniques. Molecular identification techniques in new probe-target formats, such as checkerboard DNA-DNA hybridization, permit enumeration of large numbers of species in very large numbers of samples. Digoxigenin-labeled whole… CONTINUE READING