Use of cerebrospinal fluid amyloid-β and total tau protein to predict favorable surgical outcomes in patients with idiopathic normal pressure hydrocephalus.

@article{Tarnaris2011UseOC,
  title={Use of cerebrospinal fluid amyloid-β and total tau protein to predict favorable surgical outcomes in patients with idiopathic normal pressure hydrocephalus.},
  author={Andrew Tarnaris and Ahmed K. Toma and Miles D. Chapman and Geoffrey Keir and N. D. Kitchen and Laurence Dale Watkins},
  journal={Journal of neurosurgery},
  year={2011},
  volume={115 1},
  pages={145-50}
}
OBJECT The prognostic value of CSF biomarkers in patients with idiopathic normal pressure hydrocephalus (iNPH) has not been adequately studied to date. The aim of this study was to identify CSF markers of favorable surgical outcome in patients with iNPH undergoing the insertion of a ventriculoperitoneal shunt. METHODS Ventricular CSF was collected intraoperatively from 22 patients with iNPH and enzyme-linked immunosorbent assay was used to analyze the levels of amyloid-β 1-42 (Aβ(1-42)) and… CONTINUE READING
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