Use of bovine milk concentrate containing antibody to rotavirus to treat rotavirus gastroenteritis in infants.

@article{Hilpert1987UseOB,
  title={Use of bovine milk concentrate containing antibody to rotavirus to treat rotavirus gastroenteritis in infants.},
  author={H R Hilpert and Harald Br{\"u}ssow and C. Mietens and Josette Sidoti and Larisa Lerner and Herrmann Werchau},
  journal={The Journal of infectious diseases},
  year={1987},
  volume={156 1},
  pages={
          158-66
        }
}
The use of a concentrate containing milk immunoglobulins prepared from rotavirus-hyperimmunized cows (neutralization titer, 1:6,000 for a 10% solution) to treat infants hospitalized for acute rotavirus gastroenteritis resulted in a significant (P = .008) reduction in the duration of excretion of virus. Stool samples from treated infants showed the presence of bovine milk immunoglobulins in 47% of cases and of neutralizing activity in 43% (mean neutralization titer, 1:48); stool samples from… CONTINUE READING
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