Use of bio-mimetic three-dimensional technology in therapeutics for heart disease
@article{Serpooshan2014UseOB, title={Use of bio-mimetic three-dimensional technology in therapeutics for heart disease}, author={Vahid Serpooshan and M. Zhao and Scott Metzler and K. Wei and Parisha B Shah and A. Wang and M. Mahmoudi and A. Malkovskiy and J. Rajadas and M. Butte and D. Bernstein and P. Ruiz-Lozano}, journal={Bioengineered}, year={2014}, volume={5}, pages={193 - 197 - 55} }
Due to the limited self-renewal capacity of cardiomyocytes, the mammalian heart exhibits impaired regeneration and insufficient ability to restore heart function after injury. Cardiovascular tissue engineering is currently considered as a promising alternative therapy to restore the structure and function of the failing heart. Recent evidence suggests that the epicardium may play critical roles in regulation of myocardial development and regeneration. One of the mechanisms that has been… CONTINUE READING
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