Use of bacteria in anti-cancer therapies.

@article{Ryan2006UseOB,
  title={Use of bacteria in anti-cancer therapies.},
  author={Rachel M Ryan and Jeffrey Green and Claire E. Lewis},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2006},
  volume={28 1},
  pages={84-94}
}
While a number of valid molecular targets have been discovered for tumours over the past decade, finding an effective way of delivering therapeutic genes specifically to tumours has proved more problematic. A variety of viral and non-viral delivery vehicles have been developed and applied in anti-cancer gene therapies. However, these suffer from either inefficient and/or short-lived gene transfer to target cells, instability in the bloodstream and inadequate tumour targeting. Recently, various… CONTINUE READING

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