Use of an oral stable isotope label to confirm variation in red blood cell mean age that influences HbA1c interpretation.

@article{Khera2015UseOA,
  title={Use of an oral stable isotope label to confirm variation in red blood cell mean age that influences HbA1c interpretation.},
  author={Paramjit K. Khera and Eric L. P. Smith and Christopher J Lindsell and Mary Colleen Rogge and Shannon Haggerty and David A. Wagner and Mary B. Palascak and Shilpa Mehta and Jacqueline M. Hibbert and Clinton H. Joiner and Robert S. Franco and Robert M. Cohen},
  journal={American journal of hematology},
  year={2015},
  volume={90 1},
  pages={50-55}
}
HbA1c is commonly used to monitor glycemic control. However, there is growing evidence that the relationship between HbA1c and mean blood glucose (MBG) is influenced by variation in red blood cell (RBC) lifespan in hematologically normal individuals. Correction of HbA1c for mean RBC age (MRBC ) requires a noninvasive, accurate, and affordable method to… CONTINUE READING