Use of aminopropyltransferase inhibitors and of non-metabolizable analogs to study polyamine regulation and function.

Abstract

The polyamines spermidine and spermine are essential for the growth of mammalian cells. This review describes the properties of the two aminopropyltransferases that are responsible for their biosynthesis, the synthesis and use of specific aminopropyltransferase inhibitors, and the use of analogs of the polyamines to investigate polyamine transport and… (More)

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@article{Pegg1995UseOA, title={Use of aminopropyltransferase inhibitors and of non-metabolizable analogs to study polyamine regulation and function.}, author={A. E. Pegg and Ray. G. Poulin and James K. Coward}, journal={The international journal of biochemistry & cell biology}, year={1995}, volume={27 5}, pages={425-42} }