Use of alternate promoters for tissue-specific expression of the gene coding for connexin32.

@article{Neuhaus1995UseOA,
  title={Use of alternate promoters for tissue-specific expression of the gene coding for connexin32.},
  author={Isaac M. Neuhaus and Gerhard Dahl and Ralf Werner},
  journal={Gene},
  year={1995},
  volume={158 2},
  pages={257-62}
}
The promoter of rat connexin32 (Cx32), the gap junction protein found in liver, was studied in transgenic mice. Cx32 transgenes, containing 2.5-kb of sequence upstream from the promoter, exon I, the entire 6.1-kb intron and the beginning of the coding sequence linked to the gene encoding luciferase (Luc), were found to be expressed in mouse in the same tissue-specific manner as previously reported for Cx32. Another construct lacking the promoter, but retaining 1.8 kb from the 3' end of the… CONTINUE READING