Use of allopurinol to optimize thiopurine immunomodulator efficacy in inflammatory bowel disease.

  • M P Sparrow
  • Published 2008 in Gastroenterology & hepatology

Abstract

The thiopurine immunomodulators azathioprine and 6-mercaptopurine are integral to the management of inflammatory bowel disease (IBD), particularly as corticosteroid-sparing and maintenance agents; however, up to 50% of patients do not adequately respond to these agents. Advances in pharmacogenomics and an increased understanding of thiopurine metabolism… (More)

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Cite this paper

@article{Sparrow2008UseOA, title={Use of allopurinol to optimize thiopurine immunomodulator efficacy in inflammatory bowel disease.}, author={M P Sparrow}, journal={Gastroenterology & hepatology}, year={2008}, volume={4 7}, pages={505-11} }