Use of alendronate to prevent femoral-head collapse

  title={Use of alendronate to prevent femoral-head collapse},
  author={Katherine Sole},
  journal={Nature Clinical Practice Rheumatology},
although survival has improved over recent years, morbidity remains high because of both the disease process itself and the toxicity associated with therapy. Although the underlying cause of SLE is unknown, animal studies suggest that B cells could have a key role in pathogenesis. Rituximab is a chimeric anti-CD20 antibody that reduces B-cell numbers in vivo and has been used to treat lymphoproliferative diseases in children and adults. Emerging data suggests it might also be efficacious in… CONTINUE READING