Use of alendronate in peri-implant defect regeneration.

  title={Use of alendronate in peri-implant defect regeneration.},
  author={Stephen J Meraw and Charlotte Reeve and Peter Wollan},
  journal={Journal of periodontology},
  volume={70 2},
BACKGROUND Previous studies have demonstrated an increase in bone mass and density with use of systemic alendronate sodium. This agent acts as an inhibitor of osteoclast activity, and is thought to result in more net osteoblastic activity. The objective of this study was to determine the effects of locally applied alendronate sodium on guided bone regeneration around dental implants. METHODS Six adult mongrel dogs were divided into 2 groups: one group received alendronate-coated dental… CONTINUE READING
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