Use of adverse conditions to stimulate a cellular stress response by equine articular chondrocytes.

Abstract

OBJECTIVE To determine the response of equine articular cartilage cells to heat and calcium stresses. DESIGN Analysis of newly synthesized, [35S]methionine-labeled proteins after treatment of isolated primary equine chondrocytes. PROCEDURE Primary cultures of equine articular chondrocytes were incubated at temperatures ranging from 37 to 42 C for heat… (More)

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