Use of acute phenolic denervation to show the neuronal dependence of Ca2+-induced relaxation of isolated arteries.

@article{Wang1999UseOA,
  title={Use of acute phenolic denervation to show the neuronal dependence of Ca2+-induced relaxation of isolated arteries.},
  author={Yanlin Wang and Richard D. Bukoski},
  journal={Life sciences},
  year={1999},
  volume={64 10},
  pages={887-94}
}
We recently showed that perivascular sensory nerves of mesenteric resistance arteries (MRA) express a receptor for extracellular Ca2+ (CaR) and proposed that activation of the CaR by Ca2+ causes nerve-dependent vascular relaxation. We now describe a novel procedure for acutely denervating isolated arteries and have used this method to test the hypothesis that Ca2+-induced relaxation of MRA is nerve dependent. MRA were studied using a wire myograph equipped with electrodes for electrical field… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…