Use of a quadrupole linear ion trap mass spectrometer in metabolite identification and bioanalysis.

@article{Xia2003UseOA,
  title={Use of a quadrupole linear ion trap mass spectrometer in metabolite identification and bioanalysis.},
  author={Yuan-qing Xia and Jeffrey D. Miller and Ray Bakhtiar and Ronald B. Franklin and David Q. Liu},
  journal={Rapid communications in mass spectrometry : RCM},
  year={2003},
  volume={17 11},
  pages={
          1137-45
        }
}
  • Yuan-qing Xia, Jeffrey D. Miller, +2 authors David Q. Liu
  • Published in
    Rapid communications in mass…
    2003
  • Chemistry, Medicine
  • A new type of quadrupole linear ion trap mass spectrometer, Q TRAP trade mark LC/MS/MS system (Q TRAP trade mark ), was evaluated for its performance in two studies: firstly, the in vitro metabolism of gemfibrozil in human liver microsomes, and, secondly, the quantification of propranolol in rat plasma. With the built-in information-dependent-acquisition (IDA) software, the instrument utilizes full scan MS in the ion trap mode and/or constant neutral loss scans as survey scans to trigger… CONTINUE READING

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