Use of a human microvascular endothelial cell line as a model system to evaluate cholesterol uptake.

@article{Pruckler1993UseOA,
  title={Use of a human microvascular endothelial cell line as a model system to evaluate cholesterol uptake.},
  author={James M. Pruckler and T. J. Lawley and Edwin W. Ades},
  journal={Pathobiology : journal of immunopathology, molecular and cellular biology},
  year={1993},
  volume={61 5-6},
  pages={283-7}
}
CDC/EU.HMEC-1 (HMEC-1) cells provide a reliable source of human microvascular endothelial cells free of mycoplasma and viral infection. This cell line has potential for use in the further study of the endothelial cell modification of low-density lipoproteins and for anticholesterol drug evaluation assays. HMEC-1 cells will fill a gap that is present for in vitro investigations of cholesterol metabolism in conjunction with previously established hepatic, monocytic, or macrophage cell lines. This… CONTINUE READING