Use of a highly sensitive quantitative telomerase assay in intracytoplasmic sperm injection programmes for the treatment of 47,XXY non-mosaic Klinefelter men.

@article{Yamamoto2002UseOA,
  title={Use of a highly sensitive quantitative telomerase assay in intracytoplasmic sperm injection programmes for the treatment of 47,XXY non-mosaic Klinefelter men.},
  author={Yasuhisa Yamamoto and Nikolaos Sofikitis and Apostolos I. Kaponis and John Georgiou and Dimitrios J Giannakis and Ch Mamoulakis and Dimitrios Loutradis and X Yiannakopoulos and Yasuyuki Mio and Ikuo Miyagawa and A Chatzikyziakidou},
  journal={Andrologia},
  year={2002},
  volume={34 4},
  pages={218-26}
}
We evaluated the role of the sensitive quantitative telomerase assay (SQTA) in the management of men with non-mosaic Klinefelter's syndrome (KS). Diagnostic testicular biopsy (DTB) was performed in 24 men with KS. A part of the DTB was stained and the remaining fragment was processed for the SQTA. After 3-18 months, a therapeutic testicular biopsy (TTB) was performed in the same testicle and the recovered specimens were processed to identify spermatozoa. Men with a SQTA outcome equal to 0.00… CONTINUE READING

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