Use of a Mammalian Cell Culture Benzo ( a ) pyrene Metabolism Assay for the Detection of Potential Anticarcinogens from Natural Products : Inhibition of Metabolism by Biochanin A , an Isoflavone from Trà ¬ foliumpratense L 1

@inproceedings{Cassady2006UseOA,
  title={Use of a Mammalian Cell Culture Benzo ( a ) pyrene Metabolism Assay for the Detection of Potential Anticarcinogens from Natural Products : Inhibition of Metabolism by Biochanin A , an Isoflavone from Tr{\~A} ¬ foliumpratense L 1},
  author={John M. Cassady and Thomas M. Zennie and Y Chae and Mark A. Ferin and Nuris E. Portuondo and William M. Baird},
  year={2006}
}
Based on the epidemiolÃ3gica! evidence for a relationship between consumption of certain foods and decreased cancer incidence in humans, an assay was developed to screen and fractionate plant extracts for chemopreventive potential. This assay measures effects on the metabo lism of |3H)benzo(a)pyrene [B(a)P] in hamster embryo cell cultures. Screening of… CONTINUE READING