Use of a CEPH meiotic breakpoint panel to refine the locus of limb-girdle muscular dystrophy type 1A (LGMD1A) to a 2-Mb interval on 5q31.

@article{Bartoloni1998UseOA,
  title={Use of a CEPH meiotic breakpoint panel to refine the locus of limb-girdle muscular dystrophy type 1A (LGMD1A) to a 2-Mb interval on 5q31.},
  author={Lucia Bartoloni and Stephen K. Horrigan and Kristi D. Viles and James M. Gilchrist and Jeffrey M. Stajich and Jeffery M. Vance and Larry H. Yamaoka and Margaret A. Pericak-Vance and Carol A. Westbrook and Marcy C. Speer},
  journal={Genomics},
  year={1998},
  volume={54 2},
  pages={
          250-5
        }
}
Limb-girdle muscular dystrophy type 1A (LGMD1A) is an autosomal dominant disease characterized by progressive weakness of the hip and shoulder girdle. The gene for LGMD1A had been localized to a 7-cM interval at 5q31 in a single large family (Family 39). To refine the localization of LGMD1A further and to aid in its identification, a high-resolution physical map of the locus was used to identify and provisionally localize 25 polymorphic markers. A subset of these markers was then ordered… CONTINUE READING

Citations

Publications citing this paper.