Use of Tumor Necrosis Factor Alpha Inhibitors for Inflammatory Bowel Disease Patients with Concurrent Heart Failure

@article{Jiang2017UseOT,
  title={Use of Tumor Necrosis Factor Alpha Inhibitors for Inflammatory Bowel Disease Patients with Concurrent Heart Failure},
  author={Yan-ling Jiang and O. Lin and S. Sinha},
  journal={Digestive Diseases and Sciences},
  year={2017},
  volume={62},
  pages={1597-1606}
}
BackgroundPrescribing information for tumor necrosis factor alpha (TNFα) inhibitors, a mainstay of treatment for moderate to severe inflammatory bowel disease (IBD), instructs cautious use in those with heart failure (HF). However, the limited data behind these warnings are inconclusive and should be weighed against mounting evidence demonstrating worse cardiac outcomes in active IBD.AimsTo assess whether TNFα inhibitor use is reduced in patients with IBD and HF by analyzing physician practice… Expand
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