Use of Thymidine Kinase Recombinant Adenovirus and Ganciclovir Mediated Mouse Liver Preconditioning for Hepatocyte Xenotransplantation.

@article{Moreno2017UseOT,
  title={Use of Thymidine Kinase Recombinant Adenovirus and Ganciclovir Mediated Mouse Liver Preconditioning for Hepatocyte Xenotransplantation.},
  author={Daniel Moreno and Leire Neri and Eva Vicente and Africa Vales and Rafael Aldabe},
  journal={Methods in molecular biology},
  year={2017},
  volume={1506},
  pages={179-192}
}
Hepatocyte transplantation is the best approach to maintain and propagate differentiated hepatocytes from different species. Host liver has to be adapted for transplanted hepatocytes productive engraftment and proliferation being required a chronic liver injury to eliminate host hepatocytes and provide a proliferative advantage to the transplanted… CONTINUE READING