Use of Somatosensory-Evoked Potentials and Cognitive Event-Related Potentials in Predicting Outcomes of Patients with Severe Traumatic Brain Injury

  title={Use of Somatosensory-Evoked Potentials and Cognitive Event-Related Potentials in Predicting Outcomes of Patients with Severe Traumatic Brain Injury},
  author={Henry L. Lew and Sureyya S. Dikmen and Jefferson C. Slimp and Nancy Temkin and Eun Ha Lee and David W. Newell and Lawrence R. Robinson},
  journal={American Journal of Physical Medicine \& Rehabilitation},
Lew HL, Dikmen S, Slimp J, Temkin N, Lee EH, Newell D, Robinson LR: Use of somatosensory-evoked potentials and cognitive event-related potentials in predicting outcomes of patients with severe traumatic brain injury. Am J Phys Med Rehabil 2003;82:53–61. Objective This study was performed to evaluate the usefulness of somatosensory-evoked potentials (SEPs) and cognitive event-related potentials (ERPs) in predicting functional outcomes of severe traumatic brain injury patients. Design Prospective… 
Early somatosensory evoked potential grades in comatose traumatic brain injury patients predict cognitive and functional outcome*
Day 3 somatosensory evoked potential grade had the strongest relationship with functional outcome and was related to information-processing speed, working memory, and the ability to attend to tasks 1 yr after traumatic brain injury.
Electrophysiological assessments of cognition and sensory processing in TBI: applications for diagnosis, prognosis and rehabilitation.
Prognostic Value of Somatosensory-evoked Potentials and CT Scan Evaluation in Acute Traumatic Brain Injury
Background: The aim of this study is to assess whether a complete analysis of all early cortical somatosensory-evoked potentials (SEPs) components and computed tomography (CT) scan features can
Cognitive Event-Related Potentials during the Sub-Acute Phase of Severe Traumatic Brain Injury and Their Relationship to Outcome.
Electroencephalography-based event-related potentials can index cognitive capacities in the early phase following sTBI, and the cognitive P3 component in an active design is associated with functional and cognitive outcome, demonstrating that the Cognitive P3 may yield valuable information of residual cognition and provide supplementary prognostic information.
Electrophysiologic Abnormalities of Auditory and Visual Information Processing in Patients with Traumatic Brain Injury
Although TBI patients with good recovery showed similar response accuracy when compared with control subjects, they demonstrated significantly poorer performance in both electrophysiologic and behavioral responses.
Evoked potentials for the prediction of vegetative state in the acute stage of coma
The presence of event-related evoked potentials, and particularly mismatched negativity (MMN), is a strong predictor of awakening and precludes comatose patients from moving to a permanent vegetative state (PVS).
Clinical neurophysiology of neurologic rehabilitation.
  • J. Rollnik
  • Medicine, Psychology
    Handbook of clinical neurology
  • 2019


Somatosensory and motor evoked potentials at different stages of recovery from severe traumatic brain injury.
Somatosensory evoked potentials in severe traumatic brain injury: a blinded study.
It is concluded that SSEPs correlate well with outcome and that this is not the result of investigator bias.
Somatosensory evoked potentials for prediction of outcome in acute severe brain injury.
Long-latency auditory-evoked potentials in severe traumatic brain injury.
LLAEPs can be recorded in patients with severe impairment of consciousness by means of passive paradigms and their prognostic value for late functional outcome is defined.
Event-related potentials — neurophysiological tools for predicting emergence and early outcome from traumatic coma
Highly significant correlations exist between long-latency ERP components and 3-month outcome, and pupillary response patterns, APACHE II and Glasgow Coma Scores correlate significantly with outcome, as do the retrospective measures of duration of coma and post-traumatic amnesia in survivors.
Early recovery after closed traumatic head injury: Somatosensory evoked potentials and clinical findings
Initial SEP findings correlate with long-term outcome in patients with closed head injury with DAI, and electrophysiologic recovery frequently precedes clinical recovery.
Median nerve somatosensory evoked potentials and the Glasgow Coma Scale as predictors of outcome in comatose patients with head injuries.
This study demonstrates the prognostic value of early quantitative median nerve SSEP grading for patients with head injuries who are unresponsive to commands within 1 week after the injury.
Prediction of outcome in patients with anoxic coma: a clinical and electrophysiologic study.
It is proposed that clinical examination combined with the results of EEG and somatosensory evoked potentials can be used to establish an early, definitive prognosis in a significant proportion of patients in anoxic coma.
Prediction of neuropsychiatric outcome following mild trauma brain injury: an examination of the Glasgow Coma Scale.
The results suggest that initial GCS scores do not clearly translate into neuropsychiatric sequelae at follow-up within the rubric of GCS 13-15, and a trend associating longer PTA with lower functional outcome was observed.
Disability rating scale for severe head trauma: coma to community.
The DR Scale is more sensitive than the Glasgow Outcome Scale in detecting and measuring clinical changes in individuals who have sustained severe head trauma and can be used to help identify patients most likely to benefit from intensive rehabilitation care within a hospital setting.