Use of Saliva for Early Dengue Diagnosis

  title={Use of Saliva for Early Dengue Diagnosis},
  author={Grace Siew Lian Yap and Bijon Kumar Sil and Lee-Ching Ng},
  booktitle={PLoS neglected tropical diseases},
BACKGROUND The necessity of a venous blood collection in all dengue diagnostic assays and the high cost of tests that are available for testing during the viraemic period hinder early detection of dengue cases and thus could delay cluster management. This study reports the utility of saliva in an assay that detects dengue virus (DENV)-specific immunoglobulin A (Ig A) early in the phase of a dengue infection. METHODS AND FINDINGS Using an antigen capture anti-DENV IgA (ACA) ELISA technique, we… CONTINUE READING
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