Use of Prophylactic Anticonvulsants in Neurologic Critical Care: A Critical Appraisal

  title={Use of Prophylactic Anticonvulsants in Neurologic Critical Care: A Critical Appraisal},
  author={K. Liu and A. Bhardwaj},
  journal={Neurocritical Care},
  • K. Liu, A. Bhardwaj
  • Published 2007
  • Medicine
  • Neurocritical Care
  • Seizures are commonly encountered in the setting of brain injury in neurologic critical care. Though seizure prophylaxis with the use of antiepileptic drugs is frequently utilized in variety of brain injury paradigms, it is often not based on evidence and is controversial. Significant difficulties arise from interpretation of supporting literature due to lack of definitions for early-vs.-late-seizures, variable end points with seizure prophylaxis, as well as methodologic inconsistencies for… CONTINUE READING
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