Use of Potassium Canrenoate to Suppress Ouabain-lnduced Ventricular Arrhythmias in Dogs

@inproceedings{Yeh2005UseOP,
  title={Use of Potassium Canrenoate to Suppress Ouabain-lnduced Ventricular Arrhythmias in Dogs},
  author={Billy K. Yeh and Pei-Kun Sung and Atis K. Soho},
  year={2005}
}
Potassium canrenoate, a steroidal compound and a specific antagonist of aldosterone, had (1) a potent protective effect against ouabain-induced ventricular tachycardia in intact closed-chest dogs and (2) a potent antiarrhythmic effect in abolishing ventricular bigeminy and ventricular tachycardia due to ouabain intoxication in dogs. Conversion of ouabain… CONTINUE READING