Use of PCR for the diagnosis of herpesvirus infections of the central nervous system.

@article{Debiasi2002UseOP,
  title={Use of PCR for the diagnosis of herpesvirus infections of the central nervous system.},
  author={Roberta L Debiasi and Betty K Kleinschmidt-Demasters and Adriana Weinberg and Kenneth L. Tyler},
  journal={Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology},
  year={2002},
  volume={25 Suppl 1},
  pages={S5-11}
}
Polymerase chain reaction (PCR) analysis of cerebrospinal fluid (CSF) has revolutionized the diagnosis of nervous system viral infections, particularly those caused by human herpesviruses (HHV). The PCR technique allows the detection of minute quantities of DNA or RNA in body fluids and tissues. Both fresh-frozen and formalin-fixed tissues may be utilized for PCR assays, with the latter making archival studies possible. CSF PCR has now replaced brain biopsy as the gold standard for the… CONTINUE READING

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