Use of Monte Carlo simulation to assess the pharmacodynamics of beta-lactams against Pseudomonas aeruginosa infections in children: a report from the OPTAMA program.

@article{Ellis2005UseOM,
  title={Use of Monte Carlo simulation to assess the pharmacodynamics of beta-lactams against Pseudomonas aeruginosa infections in children: a report from the OPTAMA program.},
  author={Jennifer M Ellis and Joseph Levente Kuti and David P Nicolau},
  journal={Clinical therapeutics},
  year={2005},
  volume={27 11},
  pages={1820-30}
}
BACKGROUND Assessing the likelihood of achieving bactericidal pharmacodynamic exposures against Pseudomonas aeruginosa with intravenous antimicrobial regimens would provide insights into the selection of empiric therapy in the pediatric population. OBJECTIVE The objective of this study was to use pharmacodynamic modeling to determine the likelihood of… CONTINUE READING