Use of Laboratory Markers in Addition to Symptoms for Diagnosis of Inflammatory Bowel Disease in Children: A Meta-analysis of Individual Patient Data.

@article{Holtman2017UseOL,
  title={Use of Laboratory Markers in Addition to Symptoms for Diagnosis of Inflammatory Bowel Disease in Children: A Meta-analysis of Individual Patient Data.},
  author={Gea A. Holtman and Yvonne Lisman-van Leeuwen and Andrew S Day and Ulrika Lorentzon Fagerberg and Paul Henderson and Stevan T Leach and G\ori Perminow and D. Russell Mack and Patrick Ferry van Rheenen and Els van de Vijver and David C. Wilson and J. Reitsma and Marjolein Y. Berger},
  journal={JAMA pediatrics},
  year={2017},
  volume={171 10},
  pages={
          984-991
        }
}
Importance Blood markers and fecal calprotectin are used in the diagnostic workup for inflammatory bowel disease (IBD) in pediatric patients. Any added diagnostic value of these laboratory markers remains unclear. Objective To determine whether adding laboratory markers to evaluation of signs and symptoms improves accuracy when diagnosing pediatric IBD. Data Sources A literature search of MEDLINE and EMBASE from inception through September 26, 2016. Studies were identified using indexing… CONTINUE READING
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