Use of High-Throughput Protein Array for Profiling of Differentially Expressed Proteins in Normal and Malignant Breast Tissue

@article{Hudelist2004UseOH,
  title={Use of High-Throughput Protein Array for Profiling of Differentially Expressed Proteins in Normal and Malignant Breast Tissue},
  author={Gernot Hudelist and Margit Pacher-zavisin and Christian F Singer and Tina Holper and Ernst Kubista and Martin Schreiber and Mahmood Manavi and Martin H Bilban and Klaus F Czerwenka},
  journal={Breast Cancer Research and Treatment},
  year={2004},
  volume={86},
  pages={283-293}
}
cDNA arrays provide a powerful tool to identify gene expression pattern that are potentially associated with tumor invasion and metastasis. However, genes work at the protein level and, since the transcriptional activity of a gene does not necessarily reflect cellular protein expression, the identification and quantification of proteins is essential for the understanding of molecular events leading to malignant transformation. We have therefore employed a high-throughput protein microarray… CONTINUE READING
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