Use of Germicides in the Home and the Healthcare Setting Is There a Relationship Between Germicide Use and Antibiotic Resistance?

@article{Weber2006UseOG,
  title={Use of Germicides in the Home and the Healthcare Setting Is There a Relationship Between Germicide Use and Antibiotic Resistance?},
  author={David J. Weber and William A. Rutala},
  journal={Infection Control \&\#x0026; Hospital Epidemiology},
  year={2006},
  volume={27},
  pages={1107 - 1119}
}
  • D. Weber, W. Rutala
  • Published 2006
  • Medicine
  • Infection Control & Hospital Epidemiology
Background. The spread of antibiotic-resistant pathogens represents an increasing threat in healthcare facilities. Concern has been expressed that the use of surface disinfectants and antiseptics may select for antibiotic-resistant pathogens. Objective. To review the scientific literature on whether there is a link between use of germicides (ie, disinfectants and antiseptics) and bacterial resistance to antibiotics. In addition, we will review whether antibiotic-resistant bacteria exhibit… Expand
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84 Citations
Background Citations
22
Methods Citations
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Results Citations
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84 Citations

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Citation Type

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TLDR
Evidence of less susceptible strains than the reference bacterium used in disinfectant testing, and the high percentage of qacEΔ1 gene detected are of special concern and suggests continued investigation in laboratory and in situ, not only in healthcare settings, but also in all areas of biocide usage, including different micro-organisms and biocides. Expand
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This review aims to provide up-to-date information on the use of microbicides in the healthcare settings and their impact on the microbial flora, notably in terms of emerging antimicrobial resistance. Expand
Emergence of bacterial resistance to microbicides and antibiotics
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This review aims to provide up-to-date information on the use of microbicides in the healthcare settings and their impact on the microbial flora, notably in terms of emerging antimicrobial resistance. Expand
Use of germicides in health care settings-is there a relationship between germicide use and antimicrobial resistance: A concise review.
Despite the widespread use of disinfectants and antiseptics in hospitals, acquired resistance to current disinfectants has rarely been reported. Germicides, as with medications, should only be used… Expand
Outbreaks Associated with Contaminated Antiseptics and Disinfectants
TLDR
This paper concisely reviews nosocomial outbreaks associated with the use of a microbiologically contaminated germicide and focuses on the currently recommended germicides. Expand
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TLDR
SDCs were generally effective against gram-negative bacteria with and without multidrug resistance and are therefore suitable for surface disinfection in the immediate proximity of patients. Expand
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Lemongrass EO was effective as an antibacterial and antibiofilm agent and could be a potential alternative to chemical based antimicrobial agents in both healthcare and non-healthcare environments. Expand
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