Use of Germicides in the Home and the Healthcare Setting Is There a Relationship Between Germicide Use and Antibiotic Resistance?
@article{Weber2006UseOG, title={Use of Germicides in the Home and the Healthcare Setting Is There a Relationship Between Germicide Use and Antibiotic Resistance?}, author={David J Weber and William A. Rutala}, journal={Infection Control \&\#x0026; Hospital Epidemiology}, year={2006}, volume={27}, pages={1107 - 1119} }
Background. The spread of antibiotic-resistant pathogens represents an increasing threat in healthcare facilities. Concern has been expressed that the use of surface disinfectants and antiseptics may select for antibiotic-resistant pathogens. Objective. To review the scientific literature on whether there is a link between use of germicides (ie, disinfectants and antiseptics) and bacterial resistance to antibiotics. In addition, we will review whether antibiotic-resistant bacteria exhibit…
87 Citations
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Whether mutations and thus decreased susceptibility to disinfectants occur in bacteria during disinfectant exposure are described, which is clear that reasonable use of available and effective disinfectants is needed.
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Evidence of less susceptible strains than the reference bacterium used in disinfectant testing, and the high percentage of qacEΔ1 gene detected are of special concern and suggests continued investigation in laboratory and in situ, not only in healthcare settings, but also in all areas of biocide usage, including different micro-organisms and biocides.
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This paper concisely reviews nosocomial outbreaks associated with the use of a microbiologically contaminated germicide and focuses on the currently recommended germicides.
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SDCs were generally effective against gram-negative bacteria with and without multidrug resistance and are therefore suitable for surface disinfection in the immediate proximity of patients.
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