Use of Gaseous Ozone for Eradication of Methicillin-Resistant Staphylococcus aureus From the Home Environment of a Colonized Hospital Employee

  title={Use of Gaseous Ozone for Eradication of Methicillin-Resistant Staphylococcus aureus From the Home Environment of a Colonized Hospital Employee},
  author={Hero E. L. de Boer and Carla M van Elzelingen-Dekker and Cora M F van Rheenen-Verberg and Lodewijk Spanjaard},
  journal={Infection Control \&\#x0026; Hospital Epidemiology},
  pages={1120 - 1122}
An intensive care nurse with eczema was repeatedly treated for methicillin-resistant Staphylococcus aureus (MRSA) carriage. Because cultures remained positive for MRSA, her house was investigated. Thirty-four percent of environmental samples yielded MRSA. Her children and cat were free of MRSA. The house was decontaminated with gaseous ozone. All subsequent cultures were negative for MRSA. This decontamination cost €2,000 (approximately $2,400). 

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  • N. Cimolai
  • Medicine, Biology
    European Journal of Clinical Microbiology & Infectious Diseases
  • 2008
Environmental contamination with methicillin-resistant Staphylococcus aureus is established soon after colonized or infected patients become resident and effective control measures must therefore include consideration for MRSA in the environment.

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    Clinical Microbiology Reviews
  • 2014
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Disinfecting Action of Gaseous Ozone on OXA-48-Producing Klebsiella pneumoniae Biofilm In Vitro

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Application of a novel decontamination process using gaseous ozone.

The protocol included use of a quenching agent to rapidly reduce ozone concentrations to safe levels allowing treatment times of less than 1 h for the majority of organisms tested and reductions in bacterial load of greater than 3 log values were recorded for a number of organisms.

Ozone gas is an effective and practical antibacterial agent.



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Ozone solutions should be useful in reducing the number of bacterial infections caused by inadequate disinfection against new resistant strains of methicillin-resistant Staphylococcus aureus.

Survival of Enterococci and Staphylococci on Hospital Fabrics and Plastic

The long survival of these bacteria, including MRSA and VRE, on commonly used hospital fabrics, such as scrub suits, lab coats, and hospital privacy drapes, underscores the need for meticulous contact control procedures and careful disinfection to limit the spread ofThese bacteria.

Bactericidal properties of ozone and its potential application as a terminal disinfectant.

Results of this investigation suggest that if applied after adequate cleaning ozone could be used as an effective disinfectant.

Surface germicidal effects of ozone for microorganisms.

  • Chihshan LiYu-Chun Wang
  • Biology, Medicine
    AIHA journal : a journal for the science of occupational and environmental health and safety
  • 2003
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European Antimicrobial Resistance Surveillance System shows large variations in methicillin-resistant S. aureus.

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