Use of Flow Focusing® technology to produce tobramycin-loaded PLGA microparticles for pulmonary drug delivery.


In the present work, a promising formulation of an inhaled powder based on tobramycin-loaded microparticles has been reported. Biodegradable microparticles with controlled diameters in the range of 1-5 μm and narrow size distribution were synthesized by Flow Focusing® technology. Particles production was planned and optimized with the aid of a well… (More)


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