Use of COX-II inhibitors for hand surgery patients.

  title={Use of COX-II inhibitors for hand surgery patients.},
  author={David L. Yancey and Kenneth T. Calamia},
  journal={The Journal of hand surgery},
  volume={33 10},
N p c m c d o b I a a l t l In B ri ef SPIRIN WAS INITIALLY formulated over 100 years ago as a more palatable alternative to the naturally occurring anti-inflammatory salicylate. lthough aspirin may provide relief to patients with a ariety of painful conditions, its use is limited by gastric oxicity. The mechanism of action of aspirin was not ully understood until the discovery of prostaglandins in he 1960s and the demonstration of in vivo inhibition of rostaglandin synthetase, now known as… CONTINUE READING

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