Use it or lose it: establishment and persistence of T cell memory

Abstract

Pre-existing T cell memory provides substantial protection against viral, bacterial, and parasitic infections. The generation of protective T cell memory constitutes a primary goal for cell-mediated vaccines, thus understanding the mechanistic basis of memory development and maintenance are of major importance. The widely accepted idea that T cell memory… (More)
DOI: 10.3389/fimmu.2012.00357

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